Effect of driving pressure-guided individualized PEEP in children undergoing right lateral thoracotomy cardiac surgery with cardiopulmonary bypass on postoperative atelectasis and oxygenation: a randomized controlled trial
Xinyue Chen, Haicheng Song, Mengxuan Zang, Jiahui Zhou, Yumei Liu, Yueyi Ren · 2026
Read Effect of driving pressure-guided individualized PEEP in children undergoing right lateral thoracotomy cardiac surgery with cardiopulmonary bypass on postoperative atelectasis and oxygenation: a randomized controlled trial by Xinyue Chen, Haicheng Song, Mengxuan Zang, Jiahui Zhou, Yumei Liu, Yueyi Ren (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13479712.txt.
Description
Xinyue Chen and coauthors present a 2026 randomized trial of individualized breathing support for small children during heart surgery through the right side of the chest. Collapsed lung areas after surgery are common in this setting, driven by the heart-lung machine, side positioning, and ventilation. A fixed air pressure setting may not fit every child's lungs.
Children aged six months to five years were randomized to standard protective ventilation at a fixed pressure or to pressure titrated by driving pressure measurements, repeated after positioning and after bypass. Both groups received lung recruitment maneuvers. Outcomes were collapsed lung on imaging and blood oxygenation after surgery. The trial tests whether personalizing one ventilator dial improves recovery in a fragile population.
Catalog record
| CREATOR | Xinyue Chen, Haicheng Song, Mengxuan Zang, Jiahui Zhou, Yumei Liu, Yueyi Ren |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45573 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |