The periodontal–female reproductive axis and infertility: a scoping review of epidemiological and mechanistic evidence

Isidora Mujica, María José Bendek, Andrés Celis, Angela FV Tarilonte, Aurea Simon-Soro, José A Arraztoa, Manuel B. Donoso, Sebastián E. Illanes, Lara J. Monteiro, Alejandra Chaparro · 2026

Read The periodontal–female reproductive axis and infertility: a scoping review of epidemiological and mechanistic evidence by Isidora Mujica, María José Bendek, Andrés Celis, Angela FV Tarilonte, Aurea Simon-Soro, José A Arraztoa, Manuel B. Donoso, Sebastián E. Illanes, Lara J. Monteiro, Alejandra Chaparro (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13479548.txt.

Description

Isidora Mujica and nine colleagues mapped in 2026 evidence linking gum disease to female fertility problems. Periodontitis is a common chronic inflammatory disease, and its possible ties to infertility, endometriosis, and failed implantation have drawn growing attention.

Across 22 included studies, eight population studies gave mixed results, though forward-looking data hinted at slightly lower conception chances with periodontitis. Blood-marker evidence tied gum pathogen exposure to unexplained infertility, and lab and animal work pointed to plausible body routes. Without human trials or standard exposure measures, the link stays plausible but unproven, and the authors urge trials of gum treatment before fertility treatment.

Catalog record

CREATORIsidora Mujica, María José Bendek, Andrés Celis, Angela FV Tarilonte, Aurea Simon-Soro, José A Arraztoa, Manuel B. Donoso, Sebastián E. Illanes, Lara J. Monteiro, Alejandra Chaparro
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE72 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13479548

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