Novel utilization of the seaweed-based deoxy sugars rhamnose and fucose by engineered Corynebacterium glutamicum
Ida Marie Stephansen, Luciana Fernandes Brito, Oliver Saur Auran, Synne Saether Lande, Fernando Pérez-García · 2026
Read Novel utilization of the seaweed-based deoxy sugars rhamnose and fucose by engineered Corynebacterium glutamicum by Ida Marie Stephansen, Luciana Fernandes Brito, Oliver Saur Auran, Synne Saether Lande, Fernando Pérez-García (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13479540.txt.
Description
Ida Marie Stephansen and coauthors published a 2026 biotechnology study teaching an industrial bacterium to eat seaweed sugars it normally cannot use. Corynebacterium glutamicum is a factory workhorse for amino acids and chemicals, yet it ignores rhamnose and fucose, sugars plentiful in green and brown seaweed. Widening its diet could turn abundant marine biomass into feedstock.
The team transplanted gene sets from E. coli that break down each sugar, enabling growth on either sugar alone. Transporter screening found the best import route for each: a borrowed fucose permease moved rhamnose fastest, while a native transporter handled fucose best. A toxic byproduct, lactaldehyde, forms during use of both sugars, and the study shows a native enzyme helps clear it. The work is a step toward seaweed-based bioprocessing.
Catalog record
| CREATOR | Ida Marie Stephansen, Luciana Fernandes Brito, Oliver Saur Auran, Synne Saether Lande, Fernando Pérez-García |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 53360 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |