Association between Proteinuria and Risk of Chronic Inflammatory Demyelinating Polyneuropathy/Multifocal Motor Neuropathy: A Nationwide Population-based Cohort Study
Soonwook Kwon, Ye Bin Park, Kyung-Do Han, Hye Ryoun Jang, Seung Ho Choo, Dong Wook Shin, Ju-Hong Min · 2026
Read Association between Proteinuria and Risk of Chronic Inflammatory Demyelinating Polyneuropathy/Multifocal Motor Neuropathy: A Nationwide Population-based Cohort Study by Soonwook Kwon, Ye Bin Park, Kyung-Do Han, Hye Ryoun Jang, Seung Ho Choo, Dong Wook Shin, Ju-Hong Min (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13478050.txt.
Description
Kwon and colleagues used South Korea's national health insurance database in 2026 to ask whether protein leaking into urine predicts two rare immune nerve diseases years later. Those diseases, CIDP and multifocal motor neuropathy, strip insulation from peripheral nerves and weaken muscles. The team followed adults screened in 2009, nearly 3.94 million people, through December 2020 and recorded who developed the conditions.
At screening, 2.5 percent of people had proteinuria, meaning excess protein in the urine, a sign of kidney strain. Only 210 people developed the nerve diseases during follow-up, but cases arose faster in the proteinuria group, at 1.44 per 100,000 person-years against 0.50 in the group without it. After adjustment, proteinuria still carried an adjusted hazard ratio of 2.32 for the diseases, leading the authors to suggest shared immune mechanisms between kidney and nerve.
Catalog record
| CREATOR | Soonwook Kwon, Ye Bin Park, Kyung-Do Han, Hye Ryoun Jang, Seung Ho Choo, Dong Wook Shin, Ju-Hong Min |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |