Endothelial Activation and Stress Index in Different Types of Hypertensive Pregnancy Disorders

Anna S Scholz, Lena Büchler, Annabel Kussner, Kristina Killinger, Hannah Arndt, Michael Elsässer, Thomas Luft, Cahit Birdir, Stephanie Wallwiener, Alexandra von Au · 2026

Read Endothelial Activation and Stress Index in Different Types of Hypertensive Pregnancy Disorders by Anna S Scholz, Lena Büchler, Annabel Kussner, Kristina Killinger, Hannah Arndt, Michael Elsässer, Thomas Luft, Cahit Birdir, Stephanie Wallwiener, Alexandra von Au (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13477395.txt.

Description

Anna S. Scholz and colleagues present a 2026 study of a simple blood-based index in pregnancy blood pressure disorders at Heidelberg University Hospital. The index, called EASIX, combines three routine lab values to reflect stress on blood vessel linings. Records covered deliveries from 2017 to 2022, including preeclampsia, other hypertension in pregnancy, and healthy controls.

More than 3,700 index values were available across 465 patients with preeclampsia, 197 with hypertension, and 894 controls. Values ran clearly higher in preeclampsia than in either comparison group, and higher values tracked with more organ problems. The index separated preeclampsia from other groups with moderate accuracy. Tracking across pregnancy showed values rising in healthy pregnancies, a pattern the authors map for the first time across disorder subtypes.

Catalog record

CREATORAnna S Scholz, Lena Büchler, Annabel Kussner, Kristina Killinger, Hannah Arndt, Michael Elsässer, Thomas Luft, Cahit Birdir, Stephanie Wallwiener, Alexandra von Au
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE38013
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13477395

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