Hemorrhagic Transformation Mediates Stress Hyperglycemia Effect on Functional Outcome in Minor Ischemic Stroke
Francesco Bax, Mariarosaria Valente, Federico Mazzacane, Matteo Foschi, Raffaele Ornello, Alessandro Marè, Francesco Toraldo, Caterina Del Regno, Roberto Sperotto, Antonio Taglialatela, Beatrice Del Bello, Laura Spigariol, Lucia Pavolucci, Yan Tereshko, Carolina Gentile, Francesco Janes, Simone Lorenzut, Roberto Marinig, Simona Sacco, Anna Cavallini, Gian Luigi Gigli, Giovanni Merlino, Lucio D’Anna · 2026
Read Hemorrhagic Transformation Mediates Stress Hyperglycemia Effect on Functional Outcome in Minor Ischemic Stroke by Francesco Bax, Mariarosaria Valente, Federico Mazzacane, Matteo Foschi, Raffaele Ornello, Alessandro Marè, Francesco Toraldo, Caterina Del Regno, Roberto Sperotto, Antonio Taglialatela, Beatrice Del Bello, Laura Spigariol, Lucia Pavolucci, Yan Tereshko, Carolina Gentile, Francesco Janes, Simone Lorenzut, Roberto Marinig, Simona Sacco, Anna Cavallini, Gian Luigi Gigli, Giovanni Merlino, Lucio D’Anna (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13477380.txt.
Description
Francesco Bax and colleagues report a 2026 prospective study on why stress-related high blood sugar worsens recovery after a minor stroke. The team recruited patients at five stroke centers in Italy and the United Kingdom between 2022 and 2023. All had mild strokes, little prior disability, and no large blocked vessel.
Among 1,316 patients, higher stress sugar ratios were linked to worse function at three months and to more bleeding inside the damaged brain area. Statistical mediation analysis credited that bleeding with about 15 percent of the sugar effect on poor outcome. The bleeding pathway mattered most in patients near age 60, those without diabetes, and those with higher inflammation markers. The authors say these patterns could guide patient selection for future treatment trials.
Catalog record
| CREATOR | Francesco Bax, Mariarosaria Valente, Federico Mazzacane, Matteo Foschi, Raffaele Ornello, Alessandro Marè, Francesco Toraldo, Caterina Del Regno, Roberto Sperotto, Antonio Taglialatela, Beatrice Del Bello, Laura Spigariol, Lucia Pavolucci, Yan Tereshko, Carolina Gentile, Francesco Janes, Simone Lorenzut, Roberto Marinig, Simona Sacco, Anna Cavallini, Gian Luigi Gigli, Giovanni Merlino, Lucio D’Anna |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48545 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |