Complex Percutaneous Coronary Intervention in Patients Requiring Transcatheter Aortic Valve Replacement

Thomas Gilliland, Tanush Gupta · 2026

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Description

Thomas Gilliland and Tanush Gupta reviewed in 2026 when complex coronary stenting should precede valve replacement in patients needing transcatheter aortic valve implantation. Guidelines recommend stenting first for significant proximal coronary disease, based largely on one trial.

In NOTION-3, stenting tight blockages before valve implantation cut death, heart attack, or urgent repeat procedures at two years, but complex left main disease and multiple total blockages were excluded. ACTIVATION found no difference, while FAITAVI favoured flow-guided stenting. A large trial of complete stenting after valve implantation is still running, leaving complex cases without direct trial proof.

Catalog record

CREATORThomas Gilliland, Tanush Gupta
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE15 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13476874

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