Comparison of experimental and radiobiological model-predicted survival of human laryngeal squamous cell carcinoma cells in a helium spread-out Bragg peak
Thomas Berger, Gersende Alphonse, Mario Alcocer-Avila, Caterina Monini, Charbel Koumeir, Claire Rodriguez-Lafrasse, Flavien Ralite, Nicolas Varmenot, Noel Servagent, Vincent Métivier, Ferid Haddad, Alexis Pereda, Lydia Maigne, Jean Michel Létang, Étienne Testa, Michaël Beuve · 2026
Read Comparison of experimental and radiobiological model-predicted survival of human laryngeal squamous cell carcinoma cells in a helium spread-out Bragg peak by Thomas Berger, Gersende Alphonse, Mario Alcocer-Avila, Caterina Monini, Charbel Koumeir, Claire Rodriguez-Lafrasse, Flavien Ralite, Nicolas Varmenot, Noel Servagent, Vincent Métivier, Ferid Haddad, Alexis Pereda, Lydia Maigne, Jean Michel Létang, Étienne Testa, Michaël Beuve (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13476767.txt.
Description
Thomas Berger and co-authors test helium beam therapy predictions in 2026 on radioresistant throat cancer cells. Helium beams promise sharp dose edges, yet cell data in full spread-out beams stay thin. Cells were placed at three depths in the beam and dosed from one to four gray. A simulation model predicted survival at each depth for comparison.
Measured survival at top dose sat near ten percent at all depths, with no clear depth trend. The model foresaw a fall with depth that the cells did not show. Gaps between forecast and measure ran from a fifth to over a third. Potency ratios still matched fairly between model and bench.
Catalog record
| CREATOR | Thomas Berger, Gersende Alphonse, Mario Alcocer-Avila, Caterina Monini, Charbel Koumeir, Claire Rodriguez-Lafrasse, Flavien Ralite, Nicolas Varmenot, Noel Servagent, Vincent Métivier, Ferid Haddad, Alexis Pereda, Lydia Maigne, Jean Michel Létang, Étienne Testa, Michaël Beuve |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |