High rates of SARS-CoV-2 reinfection in residents of long term care facilities despite robust spike-specific immunity following serial vaccination

Gokhan Tut, Tara Lancaster, Panagiota Sylla, David Bone, Christopher Bentley, Azar Jadir, Rachel Bruton, Katie Spencer, Soumyajit Mallick, Ahmed Elzaidi, Alexander Dowell, Mary Wu, Ruth Harvey, Edward Carr, Rupert Beale, Maria Krutikov, Oliver Stirrup, Borscha Azmi, Andrew Hayward, Andrew Copas, Lau · 2026

Read High rates of SARS-CoV-2 reinfection in residents of long term care facilities despite robust spike-specific immunity following serial vaccination by Gokhan Tut, Tara Lancaster, Panagiota Sylla, David Bone, Christopher Bentley, Azar Jadir, Rachel Bruton, Katie Spencer, Soumyajit Mallick, Ahmed Elzaidi, Alexander Dowell, Mary Wu, Ruth Harvey, Edward Carr, Rupert Beale, Maria Krutikov, Oliver Stirrup, Borscha Azmi, Andrew Hayward, Andrew Copas, Lau (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13475887.txt.

Description

Gokhan Tut and co-authors, in a 2026 study, tracked COVID-19 immunity and reinfection among older people living in long term care homes. These residents suffered very high death rates early in the pandemic. Their risk has since fallen sharply with vaccination, but how long protection lasts in this frail group is a live question.

The team measured blood and cell immunity after a fifth vaccine dose, a mixed strain mRNA shot. Immunity tied to the virus spike rose to a plateau, and stayed broadly steady for about 100 days in almost all residents. Yet over six months of follow up, 15 percent had a first infection and 30 percent were infected again. The gap between strong lab immunity and real reinfection is the study's central, sobering point for care home policy.

Catalog record

CREATORGokhan Tut, Tara Lancaster, Panagiota Sylla, David Bone, Christopher Bentley, Azar Jadir, Rachel Bruton, Katie Spencer, Soumyajit Mallick, Ahmed Elzaidi, Alexander Dowell, Mary Wu, Ruth Harvey, Edward Carr, Rupert Beale, Maria Krutikov, Oliver Stirrup, Borscha Azmi, Andrew Hayward, Andrew Copas, Lau
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE85 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13475887

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