Early neonatal death due to prenatally undiagnosed congenital subglottic stenosis in Noonan syndrome
Maolee Bhuwapathanapun, Supakorn Chaiyakarn, Atcharaporn Pongtippan, Sirawich Arunotai, Piya Chaemsaithong, Puntabut Warintaksa, Patama Promsonthi, Saisuda Noojarern, Duangrurdee Wattanasirichaigoon · 2026
Read Early neonatal death due to prenatally undiagnosed congenital subglottic stenosis in Noonan syndrome by Maolee Bhuwapathanapun, Supakorn Chaiyakarn, Atcharaporn Pongtippan, Sirawich Arunotai, Piya Chaemsaithong, Puntabut Warintaksa, Patama Promsonthi, Saisuda Noojarern, Duangrurdee Wattanasirichaigoon (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13474899.txt.
Description
Maolee Bhuwapathanapun and colleagues report in 2026 a newborn death tied to a throat narrowing missed before birth. The baby was suspected of Noonan syndrome, a gene disorder that affects growth and the heart. Delivery was by cesarean, yet the narrowing below the voice box had not shown on scans. Breathing failed at once after birth, and tube placement could not pass the block.
Post-mortem study found cartilage-based narrowing plus an abnormal link between windpipe and food pipe. Gene reading found a fresh fault in a gene called PTPN11, matching the syndrome. The case warns that lethal airway blocks can hide in this syndrome. Birth teams for such babies need airway rescue on standby.
Catalog record
| CREATOR | Maolee Bhuwapathanapun, Supakorn Chaiyakarn, Atcharaporn Pongtippan, Sirawich Arunotai, Piya Chaemsaithong, Puntabut Warintaksa, Patama Promsonthi, Saisuda Noojarern, Duangrurdee Wattanasirichaigoon |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 10958 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |