Perioperative hyperoxia versus normoxia during cardiopulmonary bypass in adult cardiac surgery: a systematic review and meta-analysis of randomized controlled trials
Najat Y. AlSejari, Batoul H. Aljaber, Saud A. Alyahya, Abdullah M. Alharran, Hamza A. Abdul-Hafez, Amal A. Alsubaiei · 2026
Read Perioperative hyperoxia versus normoxia during cardiopulmonary bypass in adult cardiac surgery: a systematic review and meta-analysis of randomized controlled trials by Najat Y. AlSejari, Batoul H. Aljaber, Saud A. Alyahya, Abdullah M. Alharran, Hamza A. Abdul-Hafez, Amal A. Alsubaiei (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13474758.txt.
Description
Najat Y. AlSejari and colleagues pool trials in 2026 on oxygen levels during heart-lung bypass in heart surgery. High oxygen has long been standard to guard against low blood oxygen, yet excess oxygen may stress tissues. Twelve randomized trials with 2,732 patients were pooled with random-effects math. Death, kidney injury, and other harms formed the main checks.
No clear gap appeared between high and standard oxygen for short- or long-term death. Kidney injury and other harms such as heart attack and stroke also looked alike. Ventilator time, intensive care stay, and hospital stay did not differ in clear ways. Either strategy seems acceptable on current proof, which invites bigger trials.
Catalog record
| CREATOR | Najat Y. AlSejari, Batoul H. Aljaber, Saud A. Alyahya, Abdullah M. Alharran, Hamza A. Abdul-Hafez, Amal A. Alsubaiei |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 63217 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |