Discrepancy between self-reported intoxication and psychomotor vigilance task performance after alcohol intake: associations with BrAC, alcohol-metabolizing genotypes, and drinking tendency

Midori Motoi, Nakyeong Shin, Momo Hama, Yukitaro Yasuda, Takayuki Nishimura, Eigo Nishimura, Hideo Toyoshima, Yuiko Araki, Takafumi Katsumura, Yali Xia, Tomoaki Ohashi, Nariaki Kuriyama, Yuna Miyauchi, Yuki Motomura, Shigekazu Higuchi · 2026

Read Discrepancy between self-reported intoxication and psychomotor vigilance task performance after alcohol intake: associations with BrAC, alcohol-metabolizing genotypes, and drinking tendency by Midori Motoi, Nakyeong Shin, Momo Hama, Yukitaro Yasuda, Takayuki Nishimura, Eigo Nishimura, Hideo Toyoshima, Yuiko Araki, Takafumi Katsumura, Yali Xia, Tomoaki Ohashi, Nariaki Kuriyama, Yuna Miyauchi, Yuki Motomura, Shigekazu Higuchi (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13474664.txt.

Description

Midori Motoi and a wide team study why felt drunkenness and alertness diverge after drinking in 2026. Ninety-three healthy adults drank a set dose based on body weight. Breath alcohol, felt intoxication, and a vigilance task were tracked over one hundred minutes. Gene types for two alcohol-breaking enzymes and usual drinking scores were also recorded.

One enzyme gene shaped how breath alcohol and felt drunkenness moved over time. Vigilance slipped with time for all, with no clear gene effect on that measure. Modeling showed breath level predicted both felt drunkenness and vigilance lapses at the forty-minute mark. Heavier usual drinkers felt less drunk at the same breath level, yet lapsed just as much.

Catalog record

CREATORMidori Motoi, Nakyeong Shin, Momo Hama, Yukitaro Yasuda, Takayuki Nishimura, Eigo Nishimura, Hideo Toyoshima, Yuiko Araki, Takafumi Katsumura, Yali Xia, Tomoaki Ohashi, Nariaki Kuriyama, Yuna Miyauchi, Yuki Motomura, Shigekazu Higuchi
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE47246
LICENSEhttps://creativecommons.org/publicdomain/zero/1.0
RIGHTSCC0
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13474664

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