Dementia transition in early cognitive decline trajectories (DETECT) study: a prospective longitudinal study protocol
Hyunju Ji, Aeyoung Cho, Harim Lee, Gyeoul Jeong, Eun Hye Hong, Kyung Hee Lee · 2026
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Description
Ji and co-authors lay out the DETECT study, a three-year Korean project tracking which older adults with mild cognitive impairment slide into dementia and which stay stable. Their 2026 protocol recruits community-dwelling adults aged 65 and over with diagnosed impairment and visits them at home annually to collect biology, psychology, and social circumstance in one frame.
The power calculation set a minimum of 60 participants, inflated to a target of 86 to absorb an expected 30% dropout over the follow-up. The measurement battery runs from questionnaires and physical tests, including gait speed over 4.5 meters at usual pace, to machine learning models that will learn the transition patterns. The gap they target is real: annual conversion from impairment to dementia runs 10 to 15%, yet modifiable and social predictors remain poorly charted.
Catalog record
| CREATOR | Hyunju Ji, Aeyoung Cho, Harim Lee, Gyeoul Jeong, Eun Hye Hong, Kyung Hee Lee |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |