Curcumin-stabilized silver nanoparticles target the Helicobacter pylori-tumor interface in gastric cancer
Komal Attri, Deepinder Sharda, Isha Tanwar, Priyanshu Gautam, Diptiman Choudhury · 2026
Read Curcumin-stabilized silver nanoparticles target the Helicobacter pylori-tumor interface in gastric cancer by Komal Attri, Deepinder Sharda, Isha Tanwar, Priyanshu Gautam, Diptiman Choudhury (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13473628.txt.
Description
Komal Attri and four colleagues developed in 2026 curcumin-stabilised silver nanoparticles aimed at Helicobacter pylori and stomach cancer cells. Chronic H. pylori infection drives lasting stomach inflammation and tumour growth by reshaping the local environment, yet treatments that hit both bacterial virulence and cancer cell survival at once are scarce. The particles, chemically made at 15 nanometres across, combine silver, valued for killing microbes, with curcumin, a plant compound that calms inflammation and fights tumours.
Against H. pylori the particles showed potent killing, at a half-maximal concentration of 3.86 micrograms per millilitre, and blocked urease, an enzyme the bacterium needs to settle in the stomach, by 80.46 percent at the highest tested dose. They also cut viability of human gastric cancer cells by 73.99 percent and showed broad effects against other strains. The authors present the formulation as a promising microbiome-directed treatment, while noting that laboratory results still need further animal testing.
Catalog record
| CREATOR | Komal Attri, Deepinder Sharda, Isha Tanwar, Priyanshu Gautam, Diptiman Choudhury |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 55 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |