A TriNetX global collaborative network retrospective cohort study on the impact of COVID-19 vaccination on juvenile idiopathic arthritis
Su-Boon Yong, Ping-Hao Chiang, Chi Ya Yang, Ji Hung Wei, Chia-Jung Li, Chih-Wei Tseng, Shiow-Ing Wang, James Cheng-Chung Wei, Jiu-Yao Wang · 2026
Read A TriNetX global collaborative network retrospective cohort study on the impact of COVID-19 vaccination on juvenile idiopathic arthritis by Su-Boon Yong, Ping-Hao Chiang, Chi Ya Yang, Ji Hung Wei, Chia-Jung Li, Chih-Wei Tseng, Shiow-Ing Wang, James Cheng-Chung Wei, Jiu-Yao Wang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13473531.txt.
Description
Su-Boon Yong and eight colleagues studied in 2026 COVID-19 vaccination in young people with juvenile idiopathic arthritis, a childhood joint disease. Using the United States TriNetX network from January 2020 through June 2023, they compared infection, service use, and death between matched groups of 652 vaccinated and 652 unvaccinated patients. A further comparison ran against influenza vaccination. The aim was to see whether vaccination protected this group or changed its care needs.
In this database study, vaccinated patients showed a higher recorded risk of SARS-CoV-2 infection and higher overall medical service use, at a hazard ratio of 2.112 for service use. No difference appeared against the influenza vaccine group, and no rise in death was found. Effects during Delta and Omicron periods were not firm. The authors warn that observational data carry confounding and selection bias, so the findings warrant deeper study of immune responses rather than any change in advice.
Catalog record
| CREATOR | Su-Boon Yong, Ping-Hao Chiang, Chi Ya Yang, Ji Hung Wei, Chia-Jung Li, Chih-Wei Tseng, Shiow-Ing Wang, James Cheng-Chung Wei, Jiu-Yao Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |