Comparative gene expression analysis of nestin-expressing hair follicle-derived cells
Mohammad Saied Salehi, Nahid Ashjazadeh, Yasaman Mohammadi, Nasrin Ghorbani, Amin Ashayerizadeh, Mohammad Reza Jafarzadeh Shirazi, Robert M. Hoffman, Sareh Pandamooz · 2026
Read Comparative gene expression analysis of nestin-expressing hair follicle-derived cells by Mohammad Saied Salehi, Nahid Ashjazadeh, Yasaman Mohammadi, Nasrin Ghorbani, Amin Ashayerizadeh, Mohammad Reza Jafarzadeh Shirazi, Robert M. Hoffman, Sareh Pandamooz (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13473501.txt.
Description
Salehi and co-authors compared the gene activity of nestin-expressing hair follicle cells, an accessible stem cell source, against bone marrow cells, dental pulp cells, astrocytes, and hypothalamic neurons. Their 2026 study measured growth-factor and neural-marker genes to judge the follicle cells' promise for nerve repair.
The follicle cells punched above their weight as growth-factor factories: their Gdnf expression ran 4.8-fold higher than in cortical astrocytes and 27-fold higher than in the hypothalamic cell line, with Bdnf comparable to bone marrow cells. Their Tubb3, a neuronal skeleton gene, ran 2.1-fold above bone marrow cells and 1.4-fold above dental pulp cells. Curiously, their own nestin marker sat lower, at 0.38-fold of dental pulp levels, hinting at readiness to mature into neurons.
Catalog record
| CREATOR | Mohammad Saied Salehi, Nahid Ashjazadeh, Yasaman Mohammadi, Nasrin Ghorbani, Amin Ashayerizadeh, Mohammad Reza Jafarzadeh Shirazi, Robert M. Hoffman, Sareh Pandamooz |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |