Association of awake prone positioning with clinical outcomes in severe immune checkpoint inhibitor-associated pneumonitis with acute hypoxemic respiratory failure: a propensity-matched retrospective cohort study
Changhao Yin, Yan Qiang, Zhen Mei, Changzhen Qi, Qian Chen, Jisheng Zhou, Xiaoyan Fan · 2026
Read Association of awake prone positioning with clinical outcomes in severe immune checkpoint inhibitor-associated pneumonitis with acute hypoxemic respiratory failure: a propensity-matched retrospective cohort study by Changhao Yin, Yan Qiang, Zhen Mei, Changzhen Qi, Qian Chen, Jisheng Zhou, Xiaoyan Fan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13473375.txt.
Description
Yin and colleagues report a 2026 study of awake prone positioning, lying face down while breathing on one's own, in severe lung inflammation caused by cancer immunotherapy drugs. The team reviewed 120 matched patients with severe disease and breathing failure at one center, comparing those who spent at least ten hours prone with those who did not.
After one week, the prone group held clearly better blood oxygen levels than the control group. Far fewer prone patients needed a breathing tube: about eighteen percent against forty-five percent. Their intensive care stays ran about four days shorter, and fewer had died by day twenty-eight, about eighteen percent against thirty-five percent. Prone positioning is free and low-tech, though only a randomized trial can confirm the benefit.
Catalog record
| CREATOR | Changhao Yin, Yan Qiang, Zhen Mei, Changzhen Qi, Qian Chen, Jisheng Zhou, Xiaoyan Fan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 78 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |