MELD 3.0: Exploring and expanding its utility beyond transplantation
Pavan Kumar Reddy Kalluru, Hassan Emad Buhulaigah, Kishan Kumar Allikesam, Deekshitha Kuchi, Abdul Muqtadir, Nirmal Onteddu, Apoorva Cherukuri, Teja Allagadda, Madhusree Kamakkagari, Hossein Rajali · 2026
Read MELD 3.0: Exploring and expanding its utility beyond transplantation by Pavan Kumar Reddy Kalluru, Hassan Emad Buhulaigah, Kishan Kumar Allikesam, Deekshitha Kuchi, Abdul Muqtadir, Nirmal Onteddu, Apoorva Cherukuri, Teja Allagadda, Madhusree Kamakkagari, Hossein Rajali (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13473250.txt.
Description
Kalluru and co-authors review MELD 3.0, the updated liver disease severity score that adds albumin and a sex adjustment, and test its usefulness far beyond transplant waiting lists. Their 2026 survey walks through heart transplantation, variceal bleeding, liver cancer with kidney failure, shunt procedures, and alcohol-associated hepatitis.
In heart transplantation the score beat older versions at predicting short-term death and intensive care use, helped by how often heart and liver failure travel together. It kept good discrimination in acute variceal hemorrhage but calibrated poorly, and in liver cancer with renal failure it was outpredicted by albumin-bilirubin models. For alcohol-associated hepatitis it surpassed older scores on mortality and dialysis need, particularly in women and malnourished patients, the groups its new variables were designed to serve.
Catalog record
| CREATOR | Pavan Kumar Reddy Kalluru, Hassan Emad Buhulaigah, Kishan Kumar Allikesam, Deekshitha Kuchi, Abdul Muqtadir, Nirmal Onteddu, Apoorva Cherukuri, Teja Allagadda, Madhusree Kamakkagari, Hossein Rajali |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |