Adaptive deep brain stimulation for dynamic gait control in Parkinson’s disease: a randomized feasibility trial
Kenneth H Louie, Jannine P Balakid, Jessica E Bath, Seongmi Song, Hamid Fekri Azgomi, Jacob H Marks, Julia T Choi, Philip A Starr, Doris D Wang · 2026
Read Adaptive deep brain stimulation for dynamic gait control in Parkinson’s disease: a randomized feasibility trial by Kenneth H Louie, Jannine P Balakid, Jessica E Bath, Seongmi Song, Hamid Fekri Azgomi, Jacob H Marks, Julia T Choi, Philip A Starr, Doris D Wang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13473014.txt.
Description
Kenneth H Louie and co-authors describe a 2026 trial of brain stimulation that adjusts to walking in people with Parkinson disease. Standard deep brain stimulation runs at a steady rate, which often helps tremor more than walking. The new method reads brain signals linked to each step and times pulses to the walking cycle. Five people with implanted devices took part in a blinded crossover test.
The team found a personal step signal for each person and built it into the implanted device. In clinic tests, the timed method gave steadier steps and better balance between the two legs. Three people finished a longer home phase with fewer falls reported. No harmful effects linked to the method appeared, which supports further study.
Catalog record
| CREATOR | Kenneth H Louie, Jannine P Balakid, Jessica E Bath, Seongmi Song, Hamid Fekri Azgomi, Jacob H Marks, Julia T Choi, Philip A Starr, Doris D Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 78851 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |