Advances in antibiofilm strategies for medical implant-associated infections: emerging technologies and translational challenges
Aditi Sharma, Bineypreet Kaur, Aditi Goyal, Purvi, Anu Priya Minhas · 2026
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Description
Sharma and colleagues present a 2026 review of strategies against biofilms on medical implants. Biofilms are slime-like communities that bacteria build on surfaces; on implants they shrug off antibiotics and immune attack, making infections hard to cure without removing the device. The review covers the main film-forming pathogens and how films develop, then surveys defenses old and new.
Defenses range from anti-stick and antimicrobial coatings to signal blockers that jam bacterial coordination, antimicrobial peptides, nanotechnology platforms, light-based therapies, and immune-targeted or smart coatings that respond to infection. Combining several in hybrid coatings is a growing theme, since films defeat single tricks. The authors close on translation: many ideas shine in the lab but stall on safety, durability, and regulation. The review gives device makers a map of what might finally reach patients.
Catalog record
| CREATOR | Aditi Sharma, Bineypreet Kaur, Aditi Goyal, Purvi, Anu Priya Minhas |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |