Unraveling the molecular Nexus of Alzheimer’s Disease and HIV encephalitis: The role of cellular senescence and transcriptional regulation

Hao Zhang, WenJun Chen, ShuYou Yuan, ShaoXiang Ding, HongXia Bao, Bo Cai, JunKai Sun, Wei Lu, HaoGang Zhu, GuoXun Shi, Eliseo A Eugenin, Eliseo A Eugenin, Eliseo A Eugenin, Eliseo A Eugenin, Eliseo A Eugenin · 2026

Read Unraveling the molecular Nexus of Alzheimer’s Disease and HIV encephalitis: The role of cellular senescence and transcriptional regulation by Hao Zhang, WenJun Chen, ShuYou Yuan, ShaoXiang Ding, HongXia Bao, Bo Cai, JunKai Sun, Wei Lu, HaoGang Zhu, GuoXun Shi, Eliseo A Eugenin, Eliseo A Eugenin, Eliseo A Eugenin, Eliseo A Eugenin, Eliseo A Eugenin (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13472368.txt.

Description

Alzheimer’s disease (AD) and HIV-associated neurocognitive disorder (HAND) share progressive cognitive decline. Their common molecular mechanisms remain poorly understood. Current therapeutic approaches lack effective biomarkers for early diagnosis and intervention. We integrated transcriptomic profiles from multiple independent cohorts across brain tissues and blood. We systematically evaluated diagnostic performance using machine learning algorithms including Random Forest, Support Vector Machine, and XGBoost.

Catalog record

CREATORHao Zhang, WenJun Chen, ShuYou Yuan, ShaoXiang Ding, HongXia Bao, Bo Cai, JunKai Sun, Wei Lu, HaoGang Zhu, GuoXun Shi, Eliseo A Eugenin, Eliseo A Eugenin, Eliseo A Eugenin, Eliseo A Eugenin, Eliseo A Eugenin
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE136 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13472368

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