Association of Staphylococcus aureus bloodstream infection with 7-day incident delirium in critically Ill adults: a propensity-weighted competing risk analysis

Jiang-Tao Deng, Wei-Jia Kong, Pu-Heng Lu, Lei Yu, Qing-Shan Zhou, Jun Jin, Xiang-Rong Nie · 2026

Read Association of Staphylococcus aureus bloodstream infection with 7-day incident delirium in critically Ill adults: a propensity-weighted competing risk analysis by Jiang-Tao Deng, Wei-Jia Kong, Pu-Heng Lu, Lei Yu, Qing-Shan Zhou, Jun Jin, Xiang-Rong Nie (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13471666.txt.

Description

Deng and co-authors asked whether the species of bacteria in a bloodstream infection changes a critically ill patient's risk of delirium, focusing on Staphylococcus aureus. Their 2026 analysis of the MIMIC-IV database covered 3,226 adults with confirmed bloodstream infection, using doubly robust weighting and competing-risk models that treat death as a rival outcome.

Staph infections made up 618 cases, 19.2% of the cohort, and they carried a distinctly higher delirium risk: a subdistribution hazard ratio of 1.39 for delirium within seven days versus Gram-negative infections. The danger concentrated early, reaching 1.60 within the first three days in the acute-window analysis. Methicillin resistance added nothing, with a ratio of 1.12 that was not significant, pointing at the species itself rather than its drug resistance.

Catalog record

CREATORJiang-Tao Deng, Wei-Jia Kong, Pu-Heng Lu, Lei Yu, Qing-Shan Zhou, Jun Jin, Xiang-Rong Nie
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE69 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13471666

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