Automated insulin delivery in type 2 diabetes: a meta-analysis of randomized trials protocol

Luis Gordillo-Rosas, Cindy Lee Cajachagua-Pucuhuaranga, Julián Santa Cruz-Venegas, Luis Mateus Urrutia-Osorio, Samir Pantoja, Jimena Lozano-Núñez, Oriana Rivera-Lozada, Cesar Bonilla-Asalde, Joshuan J. Barboza · 2026

Read Automated insulin delivery in type 2 diabetes: a meta-analysis of randomized trials protocol by Luis Gordillo-Rosas, Cindy Lee Cajachagua-Pucuhuaranga, Julián Santa Cruz-Venegas, Luis Mateus Urrutia-Osorio, Samir Pantoja, Jimena Lozano-Núñez, Oriana Rivera-Lozada, Cesar Bonilla-Asalde, Joshuan J. Barboza (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13471658.txt.

Description

Gordillo-Rosas and colleagues publish the protocol for a meta-analysis of automated insulin delivery, the artificial-pancreas systems that dose insulin from sensor readings, in type 2 diabetes. Their 2026 plan will search five databases through November 30, 2025 for randomized trials comparing these closed-loop systems with conventional insulin strategies in adults.

The review follows Cochrane methods, pools results with random-effects models, and grades certainty with GRADE. The question matters at scale: about 589 million adults live with diabetes worldwide, and over 90% of them have type 2 disease, yet automated systems are proven mainly in type 1 care. Insulin users with type 2 diabetes battle treatment inertia, low blood sugar episodes, and glucose swings the technology promises to smooth.

Catalog record

CREATORLuis Gordillo-Rosas, Cindy Lee Cajachagua-Pucuhuaranga, Julián Santa Cruz-Venegas, Luis Mateus Urrutia-Osorio, Samir Pantoja, Jimena Lozano-Núñez, Oriana Rivera-Lozada, Cesar Bonilla-Asalde, Joshuan J. Barboza
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE24 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13471658

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