Cardiac surgery as a means of reversing frailty – the CURE-Frailty Trial a prospective cohort study
V-A. Rudas, A. Lassnigg, A. Fischer-Hammerschmied, S. Ryz, J. Tichy, R. Ristl, J. Lanzerstorfer, M. H. Bernardi · 2026
Read Cardiac surgery as a means of reversing frailty – the CURE-Frailty Trial a prospective cohort study by V-A. Rudas, A. Lassnigg, A. Fischer-Hammerschmied, S. Ryz, J. Tichy, R. Ristl, J. Lanzerstorfer, M. H. Bernardi (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13471656.txt.
Description
Rudas and co-authors tested a hopeful idea: fixing the heart might reverse frailty itself, rather than frailty only blocking surgery. Their 2026 prospective cohort, the CURE-Frailty study, tracked 76 elective cardiac surgery patients with the Clinical Frailty Scale before surgery and at discharge, six months, and twelve months.
One year out, the median frailty score had dropped from 4 to 3 on the scale, a highly significant shift. Frailty improved in 35.5% of participants, worsened in only 5.2%, and held stable in 38.2% across the year. Regression singled out one helper: cardiac rehabilitation was the only factor significantly tied to improvement, leading the authors to push for routine rehab referral after discharge.
Catalog record
| CREATOR | V-A. Rudas, A. Lassnigg, A. Fischer-Hammerschmied, S. Ryz, J. Tichy, R. Ristl, J. Lanzerstorfer, M. H. Bernardi |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |