Association Between PM2.5 Components and Cerebral Hypoperfusion: A Mediation Role of Inflammatory Biomarkers
Xingyan Xu, Xinyue Lu, Nan Wang, Liuyan Zheng, Jianhui Guo, Tongjin Xu, Yiming Guo, Hao Li, Yi Yang, Le Yang · 2026
Read Association Between PM2.5 Components and Cerebral Hypoperfusion: A Mediation Role of Inflammatory Biomarkers by Xingyan Xu, Xinyue Lu, Nan Wang, Liuyan Zheng, Jianhui Guo, Tongjin Xu, Yiming Guo, Hao Li, Yi Yang, Le Yang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13471634.txt.
Description
Xu and co-authors investigate in this 2026 study whether fine air pollution particles are linked to poor blood flow in the brain. They focused on patients with intracranial arterial stenosis, a narrowing of arteries inside the skull that is common in older East Asian adults. The question was which chemical parts of the particles matter most, and whether inflammation in the blood helps explain any link.
The team studied 967 patients, estimating three years of particle exposure and measuring brain blood flow with CT scans. Overall particle exposure was strongly tied to reduced brain flow, with black carbon and organic matter together accounting for most of the combined effect. Blood cells involved in inflammation carried a small share of the link. Neutrophils mattered most. Even so, they explained just over five percent of the total effect in the mediation analysis.
Catalog record
| CREATOR | Xingyan Xu, Xinyue Lu, Nan Wang, Liuyan Zheng, Jianhui Guo, Tongjin Xu, Yiming Guo, Hao Li, Yi Yang, Le Yang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |