Implementing pharmacogenetic-guided prescribing in general practice: a qualitative process evaluation
Lisa Brunton, William Newman, John McDermott, Paul Wilson · 2026
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Description
Lisa Brunton, William Newman, John McDermott, and Paul Wilson evaluate in 2026 how gene guided prescribing was put into practice across English family medicine. Adverse reactions to medicines harm patients and raise health service costs, and testing genes before prescribing can flag risky drug choices in advance. The PROGRESS study is gauging whether such prescribing is viable in general practice, and this process evaluation ran beside it, interviewing thirty staff at twenty sites.
Clinicians saw clear value in the service yet limited testing to patients where they judged the benefit greatest. Planning rarely stretched beyond setting up the research study itself. Sites that reshaped delivery to fit their local routines found adoption easier. Running the service inside a research study, and ordinary workload pressure, both held it back. The authors draw lessons for any wider rollout.
Catalog record
| CREATOR | Lisa Brunton, William Newman, John McDermott, Paul Wilson |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44331 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |