Crosstalk-free optical indicator-actuator combinations for bidirectional optogenetics

Glena Travis, Hallur Reynisson, Anai Gonzalez-Cordero, Stefano Palomba · 2026

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Description

Bidirectional optogenetics enables simultaneous optical readout and manipulation of neural activity. However, optical crosstalk between actuators and indicators impedes clean observation and control. This review surveys genetically encoded indicators and optogenetic actuators, and the mechanisms of crosstalk, then catalogues reported crosstalk-free pairings and trade-offs.

Catalog record

CREATORGlena Travis, Hallur Reynisson, Anai Gonzalez-Cordero, Stefano Palomba
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE77 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13469994

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