MiR-7 in neurological disorders: beyond metabolic dysregulation

Cristina Puigdueta, Virginia Pardo-Marqués, Marta Torrecilla-Parra, Mario Fernández-de Frutos, José L. López-Aceituno, Carmen Zamora, Yaiza López-Manchedo, Rebeca Busto, Cristina M. Ramírez · 2026

Read MiR-7 in neurological disorders: beyond metabolic dysregulation by Cristina Puigdueta, Virginia Pardo-Marqués, Marta Torrecilla-Parra, Mario Fernández-de Frutos, José L. López-Aceituno, Carmen Zamora, Yaiza López-Manchedo, Rebeca Busto, Cristina M. Ramírez (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13468813.txt.

Description

Puigdueta and co-authors review the case for miR-7 in brain disease, in this 2026 article. MiR-7 is a tiny RNA molecule that fine-tunes gene activity. The molecule is abundant in the central nervous system. It is also unusually well conserved across species. It touches energy metabolism, inflammation, oxidative stress, and neuron survival all at once.

The review gathers evidence linking miR-7 to neurodegenerative, neurological, and psychiatric disorders, arguing it acts as a molecular node where metabolic imbalance converts into nervous-system dysfunction. Separate sections trace its confirmed gene targets and the pathways they control, then weigh its promise as a biomarker and treatment target. The authors' central point is that miR-7's reach extends well beyond metabolic regulation. It was first known for that narrower role. Therapies aimed at it could thus influence several disease processes at once.

Catalog record

CREATORCristina Puigdueta, Virginia Pardo-Marqués, Marta Torrecilla-Parra, Mario Fernández-de Frutos, José L. López-Aceituno, Carmen Zamora, Yaiza López-Manchedo, Rebeca Busto, Cristina M. Ramírez
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE79 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13468813

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