Longitudinal Exploratory Analysis of Salivary Microbiota Profiles in Patients with Oral Squamous Cell Carcinoma Before and After Surgery: A Pilot Study
Martina Coppini, Rodolfo Mauceri, Davide Vacca, Giorgio Bertolazzi, Vito Carlo Alberto Caponio, Vito Rodolico, Beatrice Belmonte, Giuseppina Campisi · 2026
Read Longitudinal Exploratory Analysis of Salivary Microbiota Profiles in Patients with Oral Squamous Cell Carcinoma Before and After Surgery: A Pilot Study by Martina Coppini, Rodolfo Mauceri, Davide Vacca, Giorgio Bertolazzi, Vito Carlo Alberto Caponio, Vito Rodolico, Beatrice Belmonte, Giuseppina Campisi (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13467391.txt.
Description
Coppini and colleagues ran a 2026 pilot study tracking saliva microbes in patients with oral squamous cell carcinoma, a mouth cancer, before and after tumor removal. Saliva testing is painless, so microbial shifts could one day aid monitoring. Sixteen patients gave samples at both time points, and ten cancer-free people served as a comparison group.
Long-read gene sequencing showed the mouth community changed after surgery. Two species were more abundant before surgery, while three others, including a Lactobacillus group, rose afterward. Microbial diversity also fell after the operation. The patients' profiles differed from the healthy group at both points, suggesting disease-linked imbalance. The authors stress the small size and missing surgical details make the results a starting hypothesis, not a clinical tool.
Catalog record
| CREATOR | Martina Coppini, Rodolfo Mauceri, Davide Vacca, Giorgio Bertolazzi, Vito Carlo Alberto Caponio, Vito Rodolico, Beatrice Belmonte, Giuseppina Campisi |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |