Acute Pain Management in Children: A Systematic Review and GRADE-Based Recommendations
Gregorio Paolo Milani, Matteo Riccò, Massimo Agosti, Rino Agostiniani, Angela Amigoni, Carla Aromatario, Egidio Barbi, Franca Benini, Antonella Cersosimo, Lucia De Zen, Daniela Dibello, Elena Chiappini, Antuan Divisic, Paola Frati, Dario Galante, Pablo Mauricio Ingelmo, Svetlana Kotzeva, Nicola Luxardo, Luca Manfredini, Carmelo Minardi, Luca Moresco, Anna Maria Moretti, Lorenzo Moscaritolo, Moreno Crotti Partel, Federico Pellegatta, Sofia Pitino, Barbara Rebesco, Emanuela Omodeo Salè, Patrizia Savant Levet, Rita Signorini, Alessandro Simonini, Marta Somaini, Agnese Suppiej, Stefano Sotgiu, Assunta Tornesello, Fabio Verdoni, Alessandro Vittori, Tiziana Zangardi, Simone Pilloni, Chiara Sassetti · 2026
Read Acute Pain Management in Children: A Systematic Review and GRADE-Based Recommendations by Gregorio Paolo Milani, Matteo Riccò, Massimo Agosti, Rino Agostiniani, Angela Amigoni, Carla Aromatario, Egidio Barbi, Franca Benini, Antonella Cersosimo, Lucia De Zen, Daniela Dibello, Elena Chiappini, Antuan Divisic, Paola Frati, Dario Galante, Pablo Mauricio Ingelmo, Svetlana Kotzeva, Nicola Luxardo, Luca Manfredini, Carmelo Minardi, Luca Moresco, Anna Maria Moretti, Lorenzo Moscaritolo, Moreno Crotti Partel, Federico Pellegatta, Sofia Pitino, Barbara Rebesco, Emanuela Omodeo Salè, Patrizia Savant Levet, Rita Signorini, Alessandro Simonini, Marta Somaini, Agnese Suppiej, Stefano Sotgiu, Assunta Tornesello, Fabio Verdoni, Alessandro Vittori, Tiziana Zangardi, Simone Pilloni, Chiara Sassetti (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13467242.txt.
Description
Gregorio Paolo Milani and a large panel of Italian pediatric specialists systematically review acute pain care in children and grade recommendations by evidence strength, in a 2026 article. Children's pain is still missed and undertreated despite good scales and medicines. Searches of two databases covered 2016 to 2025, and thirteen studies met the bar.
Validated scales proved reliable and their use tied to lower pain after treatment. Paracetamol and ibuprofen performed alike for mild to moderate pain, with any late edge for ibuprofen inconsistent across studies. Giving both cut the need for rescue doses in single studies. Play, distraction, and virtual reality eased anxiety and procedure distress, though proof quality varied.
Catalog record
| CREATOR | Gregorio Paolo Milani, Matteo Riccò, Massimo Agosti, Rino Agostiniani, Angela Amigoni, Carla Aromatario, Egidio Barbi, Franca Benini, Antonella Cersosimo, Lucia De Zen, Daniela Dibello, Elena Chiappini, Antuan Divisic, Paola Frati, Dario Galante, Pablo Mauricio Ingelmo, Svetlana Kotzeva, Nicola Luxardo, Luca Manfredini, Carmelo Minardi, Luca Moresco, Anna Maria Moretti, Lorenzo Moscaritolo, Moreno Crotti Partel, Federico Pellegatta, Sofia Pitino, Barbara Rebesco, Emanuela Omodeo Salè, Patrizia Savant Levet, Rita Signorini, Alessandro Simonini, Marta Somaini, Agnese Suppiej, Stefano Sotgiu, Assunta Tornesello, Fabio Verdoni, Alessandro Vittori, Tiziana Zangardi, Simone Pilloni, Chiara Sassetti |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36594 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |