Diagnostic Accuracy of Combined Fine-Needle Aspiration Biopsy and Ultrasonography for Malignancy in Bethesda III–IV Thyroid Nodules
Sinan Aslan, Şebnem Çimen · 2026
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Description
Sinan Aslan and Şebnem Çimen test whether pairing needle biopsy with ultrasound features beats either alone at judging uncertain thyroid nodules, in a 2026 study. The group was large: eighteen hundred patients with nodules in the two gray-zone Bethesda classes who had their thyroids removed between 2017 and 2025. One in four nodules proved malignant.
The higher gray class carried nearly double the cancer rate of the lower one. Dark appearance on ultrasound, tiny calcium specks, and ragged edges each predicted cancer on their own. Separately, biopsy and ultrasound sorted cases only weakly, while the combined model performed significantly better, giving surgeons a firmer basis for deciding who truly needs the operation.
Catalog record
| CREATOR | Sinan Aslan, Şebnem Çimen |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |