Smooth muscle actin (SMA)-negative uninodular plexiform fibromyxoma: case report of a challenging atypical presentation of a rare gastric mesenchymal tumor in a 25-year-old female

Armin Jarosch, Tomasz Dziodzio, Brigitta Globke, Robert Öllinger, Frederik Maximilian Schäfer, Kathrin Hauptmann, Sabina Niyazova, Anne Flörcken, David Horst, Abbas Agaimy, Simon Schallenberg · 2026

Read Smooth muscle actin (SMA)-negative uninodular plexiform fibromyxoma: case report of a challenging atypical presentation of a rare gastric mesenchymal tumor in a 25-year-old female by Armin Jarosch, Tomasz Dziodzio, Brigitta Globke, Robert Öllinger, Frederik Maximilian Schäfer, Kathrin Hauptmann, Sabina Niyazova, Anne Flörcken, David Horst, Abbas Agaimy, Simon Schallenberg (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13467000.txt.

Description

Armin Jarosch and co-authors report a hard-to-diagnose stomach tumor case from 2026 in a 25-year-old woman. The tumor type, plexiform fibromyxoma, is a rare benign growth that usually forms many nodules in the lower stomach and shows a marker called smooth muscle actin. Her tumor broke both rules, forming one nodule and lacking that marker.

She had vague upper belly pain and felt a firm mass herself, which measured 13 centimeters. Under the microscope the growth held bland spindle cells in loose tissue, and a panel of marker tests came back negative, ruling out look-alike tumors such as stromal tumors. A gene fusion seen in some cases was also absent. The case shows why full tissue, marker, and gene checks matter.

Catalog record

CREATORArmin Jarosch, Tomasz Dziodzio, Brigitta Globke, Robert Öllinger, Frederik Maximilian Schäfer, Kathrin Hauptmann, Sabina Niyazova, Anne Flörcken, David Horst, Abbas Agaimy, Simon Schallenberg
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE26 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13467000

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