Structural Insights into the Photoactivatable CO Release from Mn-CO and Re-CO Complexes for CO Delivery
Tao Wu, Chaoyang Shi, Chenyang Liu, Chenjie Qin, Jiangshan Wang, Yating Pang, Wenjun Gong, Wenming Wang, Hongfei Wang · 2026
Read Structural Insights into the Photoactivatable CO Release from Mn-CO and Re-CO Complexes for CO Delivery by Tao Wu, Chaoyang Shi, Chenyang Liu, Chenjie Qin, Jiangshan Wang, Yating Pang, Wenjun Gong, Wenming Wang, Hongfei Wang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13466244.txt.
Description
Tao Wu and colleagues build two metal complexes designed to release carbon monoxide when light hits them, a dosing idea for delivering the gas as a medicine, in a 2026 chemistry study. One complex centers on manganese, the other on rhenium, each holding three carbon monoxide units. Crystal analysis fixed their structures, and computer calculations helped assign their light absorption and vibration patterns.
Timed infrared readings confirmed light-triggered gas release, with the manganese version freeing its cargo much faster. Hand-off of the gas to hemoglobin was watched by light spectroscopy. The rhenium complex harmed cervical cancer cells more strongly, and light boosted that effect for both, while the manganese complex bound blood albumin more tightly.
Catalog record
| CREATOR | Tao Wu, Chaoyang Shi, Chenyang Liu, Chenjie Qin, Jiangshan Wang, Yating Pang, Wenjun Gong, Wenming Wang, Hongfei Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |