4D TEE-Guided Thrombolysis for Mechanical Mitral Valve Obstruction

Pramod Tulsidas Gitte, Umesh Khedkar, Milind Kharche · 2026

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Description

Pramod Tulsidas Gitte and colleagues show in 2026 how four-dimensional ultrasound through the gullet can guide emergency treatment for a blocked mechanical mitral valve. A 24-year-old man with a 25-millimetre valve implant arrived breathless with high valve gradients and one stuck leaflet. Standard scans proved blockage but could not tell clot from scar-like pannus, a split that decides between clot-busting drugs and surgery.

The 4D scan revealed a large mobile clot beside pannus on the ventricle side, marking clot-dominant blockage. Streptokinase clot-busting restored two-leaflet motion and cut gradients sharply. The case backs 4D imaging as the decisive step when mixed blockage hides the true cause, sparing patients an operation they may not need.

Catalog record

CREATORPramod Tulsidas Gitte, Umesh Khedkar, Milind Kharche
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE16 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13464238

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