Probable Antiphospholipid Syndrome Causing Biventricular Thrombi and Cardiogenic Shock

Parth Contractor, Joseph Deng, Liam Parker O’Neill, Esteban Davila, Manu Mysore · 2026

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Description

Parth Contractor and colleagues report a 2026 case of a 70-year-old woman whose heart chambers filled with clots amid probable antiphospholipid syndrome. Clots inside the heart are rare in this immune clotting disorder, and clots in both ventricles are rarer still. She arrived in cardiogenic shock a month after a stress-related heart muscle episode, with clots filling two thirds of both ventricles.

Support drugs and blood thinners were started, but attempts to wean support failed and the patient chose hospice care. The case exposes thin evidence beyond thinners for such extensive clots, since invasive removal carries large risks. Rapid multichamber clotting should prompt testing for this syndrome, the authors argue, even when lab proof stays probable rather than firm.

Catalog record

CREATORParth Contractor, Joseph Deng, Liam Parker O’Neill, Esteban Davila, Manu Mysore
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE13 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13464235

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