Inflammation in atherosclerosis: Drivers, mechanisms and therapies

Zihan Su, Suowen Xu · 2026

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Description

Zihan Su and Suowen Xu review inflammation as a driver of atherosclerosis, the artery-narrowing disease behind most heart attacks and strokes. Fat buildup alone no longer explains the disease, the pair argue. Vessel wall cells and immune cells keep a slow burn alive inside plaques.

Smoking, blood sugar faults, and fatty blood products all stoke that burn. A blood marker of inflammation now beats cholesterol at foretelling heart risk in some studies. Pairing fat-lowering drugs with inflammation blockers cut repeat events in trials, though infection risk needs care. Fresh tools, from stem-cell vessel models to rapid drug screens, close the survey of what care may look like next.

Catalog record

CREATORZihan Su, Suowen Xu
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE148539
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13464104

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