Fractional Flow Reserve Measurement Using Dynamic CT Perfusion Imaging in Patients with Heavy Coronary Calcification and Stent
Aaron So, Satoshi Nakamura, Masafumi Takafuji, Mustafa Haider, Christian Rogers, Patrick Teefy, Kakuya Kitagawa · 2026
Read Fractional Flow Reserve Measurement Using Dynamic CT Perfusion Imaging in Patients with Heavy Coronary Calcification and Stent by Aaron So, Satoshi Nakamura, Masafumi Takafuji, Mustafa Haider, Christian Rogers, Patrick Teefy, Kakuya Kitagawa (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13463942.txt.
Description
So and colleagues present a 2026 feasibility study of measuring fractional flow reserve, the pressure-based judge of whether a heart artery narrowing truly limits flow, from CT scans instead of a catheter. The hard cases were chosen on purpose: sixteen patients with heavy calcification and prior stents, covering twenty-four arteries, scanned with dynamic CT perfusion after a drug that stresses the heart.
An in-house algorithm computed flow reserve from how contrast brightens over time on either side of each narrowing. The values were checked against invasive catheter measurements, the clinical gold standard. Calcification and stent metal usually wreck CT accuracy, which is why this group matters. Showing the computation is feasible in the hardest arteries is the first step toward sparing such patients a catheter procedure just to decide on treatment.
Catalog record
| CREATOR | Aaron So, Satoshi Nakamura, Masafumi Takafuji, Mustafa Haider, Christian Rogers, Patrick Teefy, Kakuya Kitagawa |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |