Reference Intervals for ROTEM-tPA: Whole-Blood Fibrinolysis Assessment in Healthy Adults
Anne L. Malte, Kathrine A. Friis, Magnea Heimisdóttir, Julie Mellgaard, Johanne A. Hojbjerg, Erik L. Grove, Julie B. Larsen · 2026
Read Reference Intervals for ROTEM-tPA: Whole-Blood Fibrinolysis Assessment in Healthy Adults by Anne L. Malte, Kathrine A. Friis, Magnea Heimisdóttir, Julie Mellgaard, Johanne A. Hojbjerg, Erik L. Grove, Julie B. Larsen (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13463919.txt.
Description
Anne L. Malte and six co-authors set healthy reference ranges for ROTEM-tPA, a whole-blood test of clot breakdown. The test spins blood with an added clot-buster drug to watch how fast clots form and melt. Labs use it in research, yet no shared healthy ranges existed to judge patient results against.
The team tested 122 healthy blood donors aged twenty to sixty-nine, split evenly by sex. Repeat runs agreed closely, and readings held steady across age groups and between men and women. Ranges were set for every output, from clotting time to melt speed. Clinics now have a firm yardstick for reading the test in bleeding and clotting disorders.
Catalog record
| CREATOR | Anne L. Malte, Kathrine A. Friis, Magnea Heimisdóttir, Julie Mellgaard, Johanne A. Hojbjerg, Erik L. Grove, Julie B. Larsen |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |