The Chile BiLS case–control study of gallbladder cancer
Jill Koshiol, Vanessa Van De Wyngard, Ilona Argirion, Claudia Marco, Matías A. Pozo Diaz, Ian N. Reyes Romero, Paz Cook, Ruth M. Pfeiffer, Noldy Mardones, Karie Medina, Vanessa Olivo, Karen Pettit, Raúl Sanchez, Miguel Villaseca, Enrique Bellolio, Hector Losada, Juan Carlos Roa, Allan Hildesheim, Ma · 2026
Read The Chile BiLS case–control study of gallbladder cancer by Jill Koshiol, Vanessa Van De Wyngard, Ilona Argirion, Claudia Marco, Matías A. Pozo Diaz, Ian N. Reyes Romero, Paz Cook, Ruth M. Pfeiffer, Noldy Mardones, Karie Medina, Vanessa Olivo, Karen Pettit, Raúl Sanchez, Miguel Villaseca, Enrique Bellolio, Hector Losada, Juan Carlos Roa, Allan Hildesheim, Ma (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13463823.txt.
Description
Koshiol and a binational team described in 2026 the design of a case-control study of gallbladder cancer in Chile. The study tackles a stubborn puzzle. Most gallbladder cancer patients have gallstones. Yet only about one in a hundred people with gallstones develops this highly fatal cancer. The study recruits patients with the cancer or its precursor, high-grade dysplasia. Each case is matched with a gallstone patient who had the organ removed.
Recruitment starting in July 2022 had enrolled 196 earlier-diagnosed and 117 newly diagnosed cases by August 2025. About 96 percent of the earlier group and 92 percent of the newer group had confirmed cancer. Nearly every case gained a matched control. Participation ran near seven in ten for both groups. The region has many residents of Mapuche Indigenous ancestry. The study can therefore uncover genetic and lifestyle factors that push gallstones toward cancer.
Catalog record
| CREATOR | Jill Koshiol, Vanessa Van De Wyngard, Ilona Argirion, Claudia Marco, Matías A. Pozo Diaz, Ian N. Reyes Romero, Paz Cook, Ruth M. Pfeiffer, Noldy Mardones, Karie Medina, Vanessa Olivo, Karen Pettit, Raúl Sanchez, Miguel Villaseca, Enrique Bellolio, Hector Losada, Juan Carlos Roa, Allan Hildesheim, Ma |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |