Anthracycline-induced left atrioventricular dyssynchrony in children with leukemia: a cardiac magnetic resonance imaging study of functional and strain analysis
Yi Liao, Yang Jia, Zhigang Yang, Linjun Xie, Shiyu Xiong, Yilei Wang, Xiangao Lei, Yingkun Guo, Rong Xu · 2026
Read Anthracycline-induced left atrioventricular dyssynchrony in children with leukemia: a cardiac magnetic resonance imaging study of functional and strain analysis by Yi Liao, Yang Jia, Zhigang Yang, Linjun Xie, Shiyu Xiong, Yilei Wang, Xiangao Lei, Yingkun Guo, Rong Xu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13461419.txt.
Description
Yi Liao and colleagues used in 2026 cardiac MRI strain analysis to study how anthracycline chemotherapy disturbs the teamwork between the heart's left atrium and left ventricle in children with leukemia. Their cohort held 109 young patients treated between 2015 and 2021, split by cumulative drug dose, plus forty healthy controls of similar age. Strain measures how much heart muscle deforms with each beat, catching injury earlier than pumping fractions do.
Leukemia patients showed a paradox: their atria contracted harder by one strain measure yet emptied less completely overall, and the normal coupling between atrial and ventricular strain weakened. High-dose patients fared worse, with a coupling index climbing alongside total drug dose. The authors argue these MRI markers deserve a place in monitoring children through anthracycline treatment.
Catalog record
| CREATOR | Yi Liao, Yang Jia, Zhigang Yang, Linjun Xie, Shiyu Xiong, Yilei Wang, Xiangao Lei, Yingkun Guo, Rong Xu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |