Retrospective cohort study on prognostic factors of malignant pleural effusion secondary to pleural mesothelioma
Xin Qiao, Jing-Jing Zhang, Bin Liu, Jian-Wen Qin · 2026
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Description
Xin Qiao, Jing-Jing Zhang, Bin Liu, and Jian-Wen Qin searched in 2026 for factors that predict survival in pleural mesothelioma patients. In this cancer of the lung lining, malignant fluid builds up around the lung. Their Tianjin cohort held 71 patients diagnosed between 2015 and 2025, followed by regular telephone checks. Survival averaged a median of thirty months, and models tested clinical and lab measures, especially tests on the pleural fluid itself.
Four routine measures stood on their own. High lactate dehydrogenase in the fluid and high fibrinogen each multiplied the death hazard several-fold. Larger average platelet size also worsened outlook, and a higher lymphocyte count proved protective. All four come from ordinary baseline testing, though the authors want confirmation from larger future studies before clinical use.
Catalog record
| CREATOR | Xin Qiao, Jing-Jing Zhang, Bin Liu, Jian-Wen Qin |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30470 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |