Exploratory analysis of spread through air spaces and staple-line recurrence after wedge resection for colorectal lung metastases
Satoshi Fumimoto, Katsushi Toyohara, Nobuharu Hanaoka, Hiroko Kuwabara, Kiyoshi Sato, Takahiro Katsumata · 2026
Read Exploratory analysis of spread through air spaces and staple-line recurrence after wedge resection for colorectal lung metastases by Satoshi Fumimoto, Katsushi Toyohara, Nobuharu Hanaoka, Hiroko Kuwabara, Kiyoshi Sato, Takahiro Katsumata (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13460213.txt.
Description
Satoshi Fumimoto and colleagues explored in 2026 whether spread through air spaces predicts recurrence along the staple line after wedge removal of colorectal cancer that has spread to the lung. In this pattern, tumor cells drift into air pockets beyond the main mass. Seventy patients with seventy lesions were treated at a Japanese university hospital between 2011 and 2020. Each lesion was reviewed for spread status, surgical margin, and the ratio between tumor and margin size.
Spread appeared in about a quarter of lesions, and recurrence at the staple line in a fifth. In simple analysis, spread showed only a suggestive trend, while margin measures were significant. In the combined exploratory model, both spread and the tumor-to-margin ratio stayed associated with recurrence. The authors frame their findings as hypothesis-building for wider resections where spread is found.
Catalog record
| CREATOR | Satoshi Fumimoto, Katsushi Toyohara, Nobuharu Hanaoka, Hiroko Kuwabara, Kiyoshi Sato, Takahiro Katsumata |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32120 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |