Clinical characteristics of pulmonary hypertension associated with hereditary hemorrhagic telangiectasia treated with bevacizumab: a single-center case series

Meng Zhang, Yao Xiao, Wei Guo, Yan Wang, Hui Li, Qing Zhao, Jiancheng Han, Ye Li, Tingting Man, Dongting Liu, Yongmei Wang, Yong Chen, Jie Li, Shengchen Duan, Wenmei Zhang, Xiao Xue, Jinjiang Li, Xiaohui Hu, Wanmu Xie, Shuai Zhang, Yunxia Zhang, Zhenguo Zhai, Jun Wan · 2026

Read Clinical characteristics of pulmonary hypertension associated with hereditary hemorrhagic telangiectasia treated with bevacizumab: a single-center case series by Meng Zhang, Yao Xiao, Wei Guo, Yan Wang, Hui Li, Qing Zhao, Jiancheng Han, Ye Li, Tingting Man, Dongting Liu, Yongmei Wang, Yong Chen, Jie Li, Shengchen Duan, Wenmei Zhang, Xiao Xue, Jinjiang Li, Xiaohui Hu, Wanmu Xie, Shuai Zhang, Yunxia Zhang, Zhenguo Zhai, Jun Wan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13460051.txt.

Description

Meng Zhang leads a Beijing team reporting in 2026 on six patients whose hereditary hemorrhagic telangiectasia, an inherited vessel disorder, was complicated by pulmonary hypertension and treated with bevacizumab. Experience with this drug in that rare pairing is scarce. Charts from Beijing Anzhen Hospital between 2021 and 2024 were reviewed, and matched comparison groups with other forms of high lung blood pressure set the context. Five patients completed follow-up after a three-month starter course.

Compared with the other groups, these patients pumped far more blood per minute while their vessels offered unusually little resistance. After that course, every followed patient improved in activity class, hemoglobin, a heart strain marker, and a combined scan measure of right heart performance. Two patients improved despite starting with lower cardiac output.

Catalog record

CREATORMeng Zhang, Yao Xiao, Wei Guo, Yan Wang, Hui Li, Qing Zhao, Jiancheng Han, Ye Li, Tingting Man, Dongting Liu, Yongmei Wang, Yong Chen, Jie Li, Shengchen Duan, Wenmei Zhang, Xiao Xue, Jinjiang Li, Xiaohui Hu, Wanmu Xie, Shuai Zhang, Yunxia Zhang, Zhenguo Zhai, Jun Wan
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE32889
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13460051

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