Clinical characteristics of pure menstrual migraine and menstrually-related migraine: a cross-sectional online questionnaire study
Yanyan Zhou, Quanquan Zhang, Tian Xia, Mengyi Guo, Hongru Zhao · 2026
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Description
Yanyan Zhou and co-authors compared two forms of menstrual migraine, attacks tied to the menstrual cycle, in women attending a headache clinic. Pure menstrual migraine strikes only around menstruation, while the menstrually related form also strikes at other cycle times and is usually more disabling. Their 2026 study used online questionnaires from 430 women at a Soochow University hospital clinic. It classified 43 as pure menstrual migraine, 322 as menstrually related, and 65 as unrelated to menstruation, then compared symptoms and drug responses.
The pure group had lived with migraine for a shorter time, 6.8 years on average against 11.1 years in the related group. They also reported fewer warning symptoms before attacks, 58.1 percent versus 75.5 percent, and less nausea, eye pain, and smell sensitivity. Common anti inflammatory painkillers worked strikingly better for the pure group, relieving 96.4 percent of their attacks around menstruation against 72.8 percent in the related group.
Catalog record
| CREATOR | Yanyan Zhou, Quanquan Zhang, Tian Xia, Mengyi Guo, Hongru Zhao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |