Roles of microRNA in aging and dietary restriction-induced longevity
Jialin Fan, Guimei Zhang, Shuo Sun, Xiaowen Zhang, Yaping Li, Meng Liu, Peilin Xu, Mark Youssef, Zara Khanzada, Yifei Zhou, Yunpeng Xu · 2026
Read Roles of microRNA in aging and dietary restriction-induced longevity by Jialin Fan, Guimei Zhang, Shuo Sun, Xiaowen Zhang, Yaping Li, Meng Liu, Peilin Xu, Mark Youssef, Zara Khanzada, Yifei Zhou, Yunpeng Xu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13456651.txt.
Description
Jialin Fan leads an eleven-author review, from 2026, of tiny RNA molecules that help set how fast bodies age and how long they live. MicroRNAs are short strands that tune whole gene networks at once. Across worms, flies, and mammals, their levels shift with age, and they grip conserved pathways covering insulin signals, growth control, cell cleanup, and inflammation.
Eating less, the most reliable life-extending trick known, rewrites these RNA programs toward stress resistance and metabolic thrift. The review weighs that evidence species by species. It also tours the diagnostic promise of microRNAs floating in blood and urine, which could betray biological age without a biopsy. The authors close by imagining combined RNA networks and aging clocks as the next tools for measuring, and perhaps slowing, the aging process.
Catalog record
| CREATOR | Jialin Fan, Guimei Zhang, Shuo Sun, Xiaowen Zhang, Yaping Li, Meng Liu, Peilin Xu, Mark Youssef, Zara Khanzada, Yifei Zhou, Yunpeng Xu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |