Roles of gas molecules and related factors in knee cartilage injury and repair: a bibliometric visualization analysis of research hotspots
Dehua Liu, Yiwen Liu, Xue Wang, Xu Dong, Li Zhang, Gang Ji, Guobin Liu · 2026
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Description
Dehua Liu and six colleagues map, in a 2026 bibliometric study, the research landscape around gas molecules and knee cartilage repair. Injured cartilage heals poorly because it lacks blood vessels and nerves. Medical gases such as nitric oxide, oxygen, hydrogen, and hydrogen sulfide have emerged as candidate helpers, alongside growth factors that rebuild cartilage and inflammatory signals that destroy it.
Using visualization tools on the Web of Science database, the team charted who publishes, what clusters together, and where attention is moving. Reactive oxygen species hold a double role in the literature, damaging cartilage yet also signaling repair. Most gathered work concerns slow degeneration rather than sudden injury, a gap the authors flag. Their maps aim to show newcomers the field's core authors, hot topics, and the thin spots where gas-based repair strategies still lack proof.
Catalog record
| CREATOR | Dehua Liu, Yiwen Liu, Xue Wang, Xu Dong, Li Zhang, Gang Ji, Guobin Liu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 67912 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |