Effectiveness of THC-containing cannabis for inflammatory bowel disease: a systematic review
Sebastian Jugl, Silvia Perez-Vilar, Steven Galati, Sukhminder K Sandhu, Hung-Kai Chen, Shao-Hsuan Chang, Yehua Wang, Thorben Kurzbach, Lauren Adkins, Jingchuan Guo, Yan Wang, Almut G Winterstein, Amie Goodin · 2026
Read Effectiveness of THC-containing cannabis for inflammatory bowel disease: a systematic review by Sebastian Jugl, Silvia Perez-Vilar, Steven Galati, Sukhminder K Sandhu, Hung-Kai Chen, Shao-Hsuan Chang, Yehua Wang, Thorben Kurzbach, Lauren Adkins, Jingchuan Guo, Yan Wang, Almut G Winterstein, Amie Goodin (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13455333.txt.
Description
Sebastian Jugl and colleagues sift the findings on THC cannabis for inflammatory bowel disease in a 2026 systematic review. Many patients already use cannabis for gut symptoms, yet trials and real-world reports disagree, and recent reviews skipped real-world studies. The team searched four databases under Cochrane and PRISMA rules, keeping only peer-reviewed studies with a control group and a measured effect or safety outcome.
Eight studies qualified, four trials and four non-interventional studies, but bias ran high across them, and the non-interventional work was too biased to grade. One trial reported gains in bloating and appetite at low evidence quality. Disease activity, bowel frequency, quality of life and pain gave mixed results. Remission, weight, endoscopy scores and nausea showed no meaningful gap. The review therefore calls the findings inconclusive and asks for stronger trials before cannabis can be judged as a bowel treatment.
Catalog record
| CREATOR | Sebastian Jugl, Silvia Perez-Vilar, Steven Galati, Sukhminder K Sandhu, Hung-Kai Chen, Shao-Hsuan Chang, Yehua Wang, Thorben Kurzbach, Lauren Adkins, Jingchuan Guo, Yan Wang, Almut G Winterstein, Amie Goodin |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 59 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |