Preconception and early-pregnancy exposure to ambient air pollution and trajectories of depressive symptoms during pregnancy

Yuhong Hu, Tingyu Yang, Sandrah P Eckel, Xinci Chen, Zhongzheng Niu, Claudia M Toledo-Corral, Nathan Pavlovic, Fred Lurmann, Brendan Grubbs, Laila Al-Marayati, Erika Garcia, Santiago Morales, Jill Johnston, Genevieve F Dunton, Rima Habre, Shohreh F Farzan, Carrie Breton, Theresa M Bastain · 2026

Read Preconception and early-pregnancy exposure to ambient air pollution and trajectories of depressive symptoms during pregnancy by Yuhong Hu, Tingyu Yang, Sandrah P Eckel, Xinci Chen, Zhongzheng Niu, Claudia M Toledo-Corral, Nathan Pavlovic, Fred Lurmann, Brendan Grubbs, Laila Al-Marayati, Erika Garcia, Santiago Morales, Jill Johnston, Genevieve F Dunton, Rima Habre, Shohreh F Farzan, Carrie Breton, Theresa M Bastain (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13455309.txt.

Description

Yuhong Hu and colleagues track mood across pregnancy against air pollution exposure in a 2026 cohort study. Low mood in pregnancy follows varied paths. Dirty air has been tied to depression risk, yet little was known about whether exposure before or early in pregnancy steers which path a woman follows. The team followed 542 mostly low-income Hispanic and Latina participants in the MADRES cohort, scoring mood in each trimester and estimating home exposure to fine particles, coarse particles, nitrogen dioxide and ozone.

Four mood paths emerged, from steady low symptoms in 43.4 percent to moderate-to-high symptoms in 7.4 percent. Higher early-pregnancy nitrogen dioxide raised the relative risk of the worst path versus the steadiest path by 3.82 times, with smaller rises for fine and coarse particles. The link is observational, but it points to cleaner air in early pregnancy as one more lever for protecting maternal mood.

Catalog record

CREATORYuhong Hu, Tingyu Yang, Sandrah P Eckel, Xinci Chen, Zhongzheng Niu, Claudia M Toledo-Corral, Nathan Pavlovic, Fred Lurmann, Brendan Grubbs, Laila Al-Marayati, Erika Garcia, Santiago Morales, Jill Johnston, Genevieve F Dunton, Rima Habre, Shohreh F Farzan, Carrie Breton, Theresa M Bastain
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE53 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13455309

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