Antibiotic lock therapy for catheter-related bloodstream infections in pediatric hemato-oncology: a retrospective analysis
Besarta Kaçabeti, Remziye Semerci Şahin, Pınar Taşpınar, Gülcan Erbaş, Serap Karaman, Zeynep Karakaş, Ayper Somer, Selda Hançerli, Gülşah Tanyıldız · 2026
Read Antibiotic lock therapy for catheter-related bloodstream infections in pediatric hemato-oncology: a retrospective analysis by Besarta Kaçabeti, Remziye Semerci Şahin, Pınar Taşpınar, Gülcan Erbaş, Serap Karaman, Zeynep Karakaş, Ayper Somer, Selda Hançerli, Gülşah Tanyıldız (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13455287.txt.
Description
Kaçabeti and colleagues looked at records of antibiotic lock therapy for bloodstream infections in pediatric blood cancer patients at one center, from 2021 to 2024. Lock therapy fills a child's central line with strong antibiotic to clear it from inside. Of 53 children, 47 got lock therapy and six went straight to catheter removal.
Seventy infection episodes occurred among the 47 treated patients, a rate of 12.79 per 1,000 catheter-days in the cohort. Lock therapy succeeded in 70.2 percent, saving the line in 33 of 47 children who received it. Coagulase-negative staphylococci were the commonest culprits, while gram-negative organisms dominated the failures that still needed removal after lock treatment. Infections clustered between days 11 and 45 of catheter use, a high-risk window the authors say warrants closer monitoring and earlier intervention.
Catalog record
| CREATOR | Besarta Kaçabeti, Remziye Semerci Şahin, Pınar Taşpınar, Gülcan Erbaş, Serap Karaman, Zeynep Karakaş, Ayper Somer, Selda Hançerli, Gülşah Tanyıldız |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 46 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |