Air pollution and disease progression among patients with primary glomerular disease: an expanded study with extended follow-up
Jonathan P. Troost, Abhijit V. Kshirsagar, William E. Smoyer, Jon Klein, Michael L. Merchant, Margaret Helmuth, Laura H. Mariani, Matthias Kretzler, Abigail R. Smith, Forrest Lacey, Lawrence S. Engel, Howard Trachtman, Cassandra R. O’Lenick · 2026
Read Air pollution and disease progression among patients with primary glomerular disease: an expanded study with extended follow-up by Jonathan P. Troost, Abhijit V. Kshirsagar, William E. Smoyer, Jon Klein, Michael L. Merchant, Margaret Helmuth, Laura H. Mariani, Matthias Kretzler, Abigail R. Smith, Forrest Lacey, Lawrence S. Engel, Howard Trachtman, Cassandra R. O’Lenick (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13455273.txt.
Description
Troost and collaborators widened their earlier air pollution study in 925 children and adults with primary glomerular kidney diseases. They re-ran the analysis with a national air research dataset and longer follow-up. More pollutants were tested against disease decline. Decline meant a 40 percent drop in filtering rate or kidney failure.
The new pollutant data repeated the original adverse findings for fine particles and black carbon in this patient cohort with extended observation. Nitrogen dioxide emerged as an additional culprit, with a hazard ratio of 1.12 per doubling of exposure for decline in the survival models. Specific chemical components of fine particulate matter also showed new associations with faster decline in the wider analysis reported. The authors argue the replication across independent exposure datasets strengthens the case that air quality is a modifiable driver of glomerular disease outcomes.
Catalog record
| CREATOR | Jonathan P. Troost, Abhijit V. Kshirsagar, William E. Smoyer, Jon Klein, Michael L. Merchant, Margaret Helmuth, Laura H. Mariani, Matthias Kretzler, Abigail R. Smith, Forrest Lacey, Lawrence S. Engel, Howard Trachtman, Cassandra R. O’Lenick |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |